Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cdx2 regulation of posterior development through non-Hox targets.

Development (Cambridge, England) - 1 Dec 2009

Savory Joanne G A, Bouchard Nathalie, Pierre Vicki, Rijli Filippo M, De Repentigny Yves, Kothary Rashmi, Lohnes David

Abstract excerpt

The homeodomain transcription factors Cdx1, Cdx2 and Cdx4 play essential roles in anteroposterior vertebral patterning through regulation of Hox gene expression. Cdx2 is also expressed in the trophectoderm commencing at E3.5 and plays an essential role in implantation, thus precluding assessment of the cognate-null phenotype at later stages. Cdx2 homozygous null embryos generated by tetraploid aggregation exhibit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to CDX2 Transcription Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

Share to Tamoxifen

Share to Wnt Proteins

Share to Wnt3 Protein

Share to Wnt3A Protein

Source

Identifiers

PMID: 19906845
DOI: 10.1242/dev.041582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cdx2 regulation of posterior development through non-Hox targets.PMID 19906845Read ↗

Cdx2 is essential for axial elongation in mouse development.Semantic proximity Read ↗

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.Semantic proximity Read ↗

Regulation of axial elongation by Cdx.Semantic proximity Read ↗

Concerted involvement of Cdx<i>/</i>Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zoneSemantic proximity Read ↗

The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice.Semantic proximity Read ↗

Cdx4 is a Cdx2 target gene.Semantic proximity Read ↗

Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.Semantic proximity Read ↗

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis.Semantic proximity Read ↗

Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endodermSemantic proximity Read ↗

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration.Semantic proximity Read ↗

Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment.Semantic proximity Read ↗

The Lineage-Specific Transcription Factor CDX2 Navigates Dynamic Chromatin to Control Distinct Stages of Intestine DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.