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Article

Impact of the hypoxia-inducible factor-1 α (HIF1A) Pro582Ser polymorphism on diabetes nephropathy.

Diabetes care - 1 Feb 2013

Gu Harvest F, Zheng Xiaowei, Abu Seman Norhashimah, Gu Tianwei, Botusan Ileana Ruxandra, Sunkari Vivekananda Gupta, Lokman Ezarul Faradianna, Brismar Kerstin, Catrina Sergiu-Bogdan

Abstract excerpt

OBJECTIVE: Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS: In 1,165 American type 1 diabetic patients with and without DN selected from the Genetics of Kidneys in Diabetes (GoKinD) study, the HIF1A genetic polymorphisms were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22991450
DOI: 10.2337/dc12-1125
PMCID: PMC3554309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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