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Article

Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men.

Journal of hepatology - 1 Jan 2013

Borkham-Kamphorst Erawan, Zimmermann Henning W, Gassler Nikolaus, Bissels Ute, Bosio Andreas, Tacke Frank, Weiskirchen Ralf, Kanse Sandip M

Abstract excerpt

BACKGROUND & AIMS: Factor VII activating protease (FSAP) is a circulating serine protease produced in the liver. A single nucleotide polymorphism (G534E, Marburg I, MI-SNP) in the gene encoding FSAP (HABP2) leads to lower enzymatic activity and is associated with enhanced liver fibrosis in humans...

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Source

Identifiers

PMID: 22989567
DOI: 10.1016/j.jhep.2012.09.007

Genes

HABP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22989567-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men.PMID 22989567Read ↗

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