Article
Structure-function analysis of factor VII activating protease (FSAP): sequence determinants for heparin binding and cellular functions.
FEBS letters - 18 Jun 2009
Muhl Lars, Hersemeyer Karin, Preissner Klaus T, Weimer Thomas, Kanse Sandip M
Abstract excerpt
Factor VII activating protease (FSAP) is associated with cardiovascular diseases and liver fibrosis. To understand the regulation of its proteolytic activity we have characterized recombinant FSAP-mutants over-expressed in HEK-293 cells. The secreted FSAP-protein concentration correlated inversel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
