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Article

Factor VII-activating protease (FSAP): vascular functions and role in atherosclerosis.

Thrombosis and haemostasis - 1 Feb 2008

Kanse Sandip M, Parahuleva Mariana, Muhl Lars, Kemkes-Matthes Bettina, Sedding Daniel, Preissner Klaus T

Abstract excerpt

FSAP is a plasma serine protease for which a potential role in the regulation of coagulation and fibrinolysis is postulated, based on its property to activate factor VII (FVII) as well as pro-urokinase (uPA). In clinical studies, the G534E single nucleotide polymorphism (Marburg I) of FSAP has been linked to late complications of atherothrombosis and is associated with a low proteolytic activity, particularly,...

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Identifiers

PMID: 18278176
DOI: 10.1160/TH07-10-0640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Factor VII-activating protease (FSAP): vascular functions and role in atherosclerosis.PMID 18278176Read ↗

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