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Article

The factor VII-activating protease (FSAP) enhances the activity of bone morphogenetic protein-2 (BMP-2).

The Journal of biological chemistry - 8 Mar 2013

Roedel Elfie Kathrin, Schwarz Elisabeth, Kanse Sandip Madhav

Abstract excerpt

Factor VII-activating protease (FSAP) is a circulating protease involved in the pathogenesis of atherosclerosis, calcification, and fibrotic processes. To understand how FSAP controls the balance of local growth factors, we have investigated its effect on the regulation of bone morphogenetic proteins (BMPs). BMP-2 is produced as a large pro-form and secreted as a mature heparin-binding growth factor after...

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Identifiers

PMID: 23341458
DOI: 10.1074/jbc.M112.433029
PMCID: PMC3591628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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