Article
The development and characterization of encephalitogenic cloned T cells specific for myelin proteolipid protein.
Journal of neuroimmunology - 1 Feb 1990
van der Veen R C, Trotter J L, Hickey W F, Kapp J A
Abstract excerpt
T-cell clones have been isolated from SJL/J mice after immunization with myelin proteolipid protein (PLP). The cloned cells responded strongly to PLP stimulation in vitro as well as to the synthetic PLP-related peptide 139-151. The response to PLP is Ia mediated, since it was inhibited by monoclo...
Topics
- Animals
- Antibodies, Monoclonal
- Cell Division
- Central Nervous System
- Clone Cells
- Encephalitis
- Female
- Haplotypes
- Histocompatibility Antigens Class II
- Immunization, Passive
- Mice
- Mice, Inbred Strains
- Myelin Proteins
- Phenotype
- T-Lymphocytes