Article
Autopathogenic T helper cell type 1 (Th1) and protective Th2 clones differ in their recognition of the autoantigenic peptide of myelin proteolipid protein.
The Journal of experimental medicine - 15 Sept 1997
Das M P, Nicholson L B, Greer J M, Kuchroo V K
Abstract excerpt
We previously generated a panel of T helper cell 1 (Th1) clones specific for an encephalitogenic peptide of myelin proteolipid protein (PLP) peptide 139-151 (HSLGKWLGHPDKF) that induces experimental autoimmune encephalomyelitis (EAE) upon adoptive transfer. In spite of the differences in their T...
Topics
- Adoptive Transfer
- Amino Acid Sequence
- Animals
- Autoantigens
- Autoimmunity
- Clone Cells
- Cross Reactions
- Cytokines
- Encephalomyelitis, Autoimmune, Experimental
- Immunization
- Lymphocyte Activation
- Mice
- Molecular Sequence Data
- Myelin Proteolipid Protein
- Peptide Fragments