Article
Myelin basic protein specific T cell lines and clones derived from the CNS of rats with EAE only recognize encephalitogenic epitopes.
Journal of neuroscience research - 1 Oct 1991
Bourdette D N, Vainiene M, Morrison W, Jones R, Turner M J, Hashim G A, Vandenbark A A, Offner H
Abstract excerpt
The epitope specificities of myelin basic protein (BP) specific T cell lines derived from the spinal cords (SC) and lymph nodes (LN) of rats with experimental autoimmune encephalomyelitis (EAE) were compared. To induce EAE, Lewis rats were immunized with guinea pig (GP)-BP and complete Freund's a...
Topics
- Animals
- Antibody Specificity
- Cell Division
- Cell Line
- Encephalomyelitis, Autoimmune, Experimental
- Epitopes
- Leukocytes, Mononuclear
- Lymph Nodes
- Male
- Mycobacterium
- Myelin Basic Protein
- Phenotype
- Rats
- Spinal Cord
- T-Lymphocytes