Article
Peptide 53-78 of myelin P2 protein is a T cell epitope for the induction of experimental autoimmune neuritis.
Cellular immunology - 1 Feb 1991
Rostami A, Gregorian S K
Abstract excerpt
We have recently described the clinical and pathological features of experimental autoimmune neuritis (EAN) in Lewis rats inoculated with varying doses of a synthetic peptide corresponding to the amino acid residues 53-78 of bovine P2 protein (SP-26). Immunization with this synthetic peptide was able to induce severe clinical and pathological characteristics of EAN. We are now reporting that, SP-26 T cell lines...
Topics
- Animals
- Cell Line
- Epitopes
- Female
- Immunotherapy, Adoptive
- Myelin Basic Protein
- Myelin P2 Protein
- Neuritis, Autoimmune, Experimental
- Peptide Fragments
- Phenotype
- Rats
- Rats, Inbred Lew
