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Article

Follicular variant of papillary thyroid carcinoma presenting as toxic nodule in an adolescent: coexistent polymorphism of the TSHR and Gsα genes.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2013

Ruggeri Rosaria Maddalena, Campennì Alfredo, Giovinazzo Salvatore, Saraceno Giovanna, Vicchio Teresa Manuela, Carlotta Dario, Cucinotta Maria Paola, Micali Carmelo, Trimarchi Francesco, Tuccari Giovanni, Baldari Sergio, Benvenga Salvatore

Abstract excerpt

BACKGROUND: Autonomously functioning, "hot", thyroid nodules are not common in children and adolescents. Such nodules are not considered alarming because they are assumed to be benign adenomas. Herein, we present a 15-year-old girl with a papillary thyroid carcinoma of 3.5 cm in diameter, which was functionally autonomous and scintigraphically hot. PATIENT FINDINGS: The patient, initially referred to our...

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Source

Identifiers

PMID: 22985488
DOI: 10.1089/thy.2012.0279

Genes

TSHR
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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