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Article

Mitotically Active Follicular Nodule in Early Childhood: A Case Report with a Novel Mutation in the Thyroglobulin Gene

Journal of clinical research in pediatric endocrinology - 5 Sept 2024

Kızılcan Çetin Sirmen, Aycan Zehra, Şıklar Zeynep, Dizbay Sak Serpil, Ceylaner Serdar, Özsu Elif, Berberoğlu Merih

Abstract excerpt

Dyshormonogenesis (DG) is the failure of thyroid hormone production due to a defect in thyroid hormonogenesis. Loss-of-function mutations in the thyroglobulin (TG) gene are a cause of DG, leading to gland stimulation by thyroid-stimulating hormone (TSH), resulting in goiter. We report a mitotically active follicular nodule in an 11-year-old female with a novel mutation in the TG gene. The patient had been under...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36453602
DOI: 10.4274/jcrpe.galenos.2022.2022-8-20
PMCID: PMC11590766

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