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Article

Enhanced phosphoserine insertion during Escherichia coli protein synthesis via partial UAG codon reassignment and release factor 1 deletion.

FEBS letters - 19 Oct 2012

Heinemann Ilka U, Rovner Alexis J, Aerni Hans R, Rogulina Svetlana, Cheng Laura, Olds William, Fischer Jonathan T, Söll Dieter, Isaacs Farren J, Rinehart Jesse

Abstract excerpt

Genetically encoded phosphoserine incorporation programmed by the UAG codon was achieved by addition of engineered elongation factor and an archaeal aminoacyl-tRNA synthetase to the normal Escherichia coli translation machinery (Park et al., 2011) Science 333, 1151). However, protein yield suffer...

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Identifiers

PMID: 22982858
DOI: 10.1016/j.febslet.2012.08.031
PMCID: PMC3473164

Genes

WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22982858-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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