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Article

Toward the experimental codon reassignment in vivo: protein building with an expanded amino acid repertoire.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 1999

Budisa N, Minks C, Alefelder S, Wenger W, Dong F, Moroder L, Huber R

Abstract excerpt

The high precision and fidelity of the genetic message transmission are ensured by numerous proofreading steps, from DNA replication and transcription to protein translation. The key event for translational fidelity is the proper codon assignment for 20 canonical amino acids. An experimental codon reassignment is possible for noncanonical amino acids in vivo using artificially constructed expression hosts under...

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PMID: 9872928
DOI: 10.1096/fasebj.13.1.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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