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Article

Atypical GATA protein TRPS1 plays indispensable roles in mouse two-cell embryo

12 Feb 2019

Abstract excerpt

Zygotic genome activation (ZGA) is one of the most critical events at the beginning of mammalian preimplantation embryo development (PED). The mechanisms underlying mouse ZGA remain unclear although it has been widely studied. In the present study, we identified that tricho-rhino-phalangeal syndrome 1 (TRPS1), an atypical GATA family member, is an important factor for ZGA in mouse PED. We found that the Trps1...

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PMID: 30712485
DOI: 10.1080/15384101.2019.1577650

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