Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of HPA axis genetics and early life stress shapes emotion recognition in healthy adults.

Psychoneuroendocrinology - 1 Jan 2019

Hartling Corinna, Fan Yan, Weigand Anne, Trilla Irene, Gärtner Matti, Bajbouj Malek, Dziobek Isabel, Grimm Simone

Abstract excerpt

BACKGROUND: Early life stress (ELS) affects facial emotion recognition (FER), as well as the underlying brain network. However, there is considerable inter-individual variability in these ELS-caused alterations. As the hypothalamic-pituitary-adrenal (HPA) axis is assumed to mediate neural and behavioural sequelae of ELS, the genetic disposition towards HPA axis reactivity might explain differential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adverse Childhood Experiences
Share to CRF Receptor, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Facial Expression

Share to Genetic Profile

Share to Hypothalamo-Hypophyseal System

Share to Pituitary-Adrenal System

Share to Receptors, Corticotropin-Releasing Hormone

Share to Tacrolimus Binding Proteins

Source

Identifiers

PMID: 30172967
DOI: 10.1016/j.psyneuen.2018.08.030

Genes

FER
CRHR1
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of HPA axis genetics and early life stress shapes emotion recognition in healthy adults.PMID 30172967Read ↗

Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function.Semantic proximity Read ↗

Genetics of emotion.Semantic proximity Read ↗

HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.Semantic proximity Read ↗

Psychiatric symptoms in adolescents: FKBP5 genotype--early life adversity interaction effects.Semantic proximity Read ↗

Cumulative genetic effects of HPA axis on social phobia scrutiny fear: psychoticism and social face as mediators.Semantic proximity Read ↗

The Interaction between Childhood Bullying and the FKBP5 Gene on Psychotic-Like Experiences and Stress Reactivity in Real Life.Semantic proximity Read ↗

Early-Life Adversity Interacts with FKBP5 Genotypes: Altered Working Memory and Cardiac Stress Reactivity in the Oklahoma Family Health Patterns Project.Semantic proximity Read ↗

FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity.Semantic proximity Read ↗

HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescentsSemantic proximity Read ↗

Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD.Semantic proximity Read ↗

Risk and resilience: genetic and environmental influences on development of the stress response.Semantic proximity Read ↗

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.