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Article

FKBP5 interacts with maltreatment in children with extreme, pervasive, and persistent aggression.

Psychiatry research - 30 Aug 2016

Bryushkova Lyubov, Zai Clement, Chen Sheng, Pappa Irene, Mileva Viara, Tiemeier Henning, Bakermans-Kranenburg Marian, Kennedy James L, Beitchman Joseph H

Abstract excerpt

Genetic variation in stress response protein FKBP5 is associated with adult psychopathology, but little is known about its role in children's mental health. 5 polymorphisms were genotyped in 170 high aggression cases and 170 age- and sex-matched controls. The rs9470080 polymorphism was associated with physiological anxiety, while rs4713916 polymorphism interacted with maltreatment to influence externalizing...

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Source

Identifiers

PMID: 27315459
DOI: 10.1016/j.psychres.2015.09.052

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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