Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood.

doi:10.1016/j.euroneuro.2013.12.001

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Article

Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jun 2014

Buchmann Arlette F, Holz Nathalie, Boecker Regina, Blomeyer Dorothea, Rietschel Marcella, Witt Stephanie H, Schmidt Martin H, Esser Günter, Banaschewski Tobias, Brandeis Daniel, Zimmermann Ulrich S, Laucht Manfred

Abstract excerpt

Recent research suggests an important role of FKBP5, a glucocorticoid receptor regulating co-chaperone, in the development of stress-related diseases such as depression and anxiety disorders. The present study aimed to replicate and extend previous evidence indicating that FKBP5 polymorphisms moderate hypothalamus-pituitary-adrenal (HPA) function by examining whether FKBP5 rs1360780 genotype and different...

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PMID: 24411633
DOI: 10.1016/j.euroneuro.2013.12.001

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FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Moderating role of FKBP5 genotype in the impact of childhood adversity on cortisol stress response during adulthood.PMID 24411633Read ↗

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