Article
FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.
Psychoneuroendocrinology - 1 Jul 2016
Watkins Laura E, Han Shizhong, Harpaz-Rotem Ilan, Mota Natalie P, Southwick Steven M, Krystal John H, Gelernter Joel, Pietrzak Robert H
Abstract excerpt
Polymorphisms in the FK506 Binding Protein 5 (FKBP5) gene may interact with childhood abuse to increase risk of developing posttraumatic stress disorder (PTSD) symptoms. The objective of this study was to examine the relationship of four previously identified FKBP5 putative risk SNPs (rs9296158, rs3800373, rs1360780, rs947008), childhood abuse, and lifetime PTSD symptoms, including contemporary phenotypic models...
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