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Article

Ghrelin receptor regulates adipose tissue inflammation in aging.

Aging - 1 Jan 2016

Lin Ligen, Lee Jong Han, Buras Eric D, Yu Kaijiang, Wang Ruitao, Smith C Wayne, Wu Huaizhu, Sheikh-Hamad David, Sun Yuxiang

Abstract excerpt

Aging is commonly associated with low-grade adipose inflammation, which is closely linked to insulin resistance. Ghrelin is the only circulating orexigenic hormone which is known to increase obesity and insulin resistance. We previously reported that the expression of the ghrelin receptor, growth hormone secretagogue receptor (GHS-R), increases in adipose tissues during aging, and old Ghsr(-/-) mice exhibit a...

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Identifiers

PMID: 26837433
DOI: 10.18632/aging.100888
PMCID: PMC4761721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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