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Article

Stop codons in bacteria are not selectively equivalent.

Biology direct - 13 Sept 2012

Povolotskaya Inna S, Kondrashov Fyodor A, Ledda Alice, Vlasov Peter K

Abstract excerpt

BACKGROUND: The evolution and genomic stop codon frequencies have not been rigorously studied with the exception of coding of non-canonical amino acids. Here we study the rate of evolution and frequency distribution of stop codons in bacterial genomes. RESULTS: We show that in bacteria stop codons evolve slower than synonymous sites, suggesting the action of weak negative selection. However, the frequency of stop...

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Identifiers

PMID: 22974057
DOI: 10.1186/1745-6150-7-30
PMCID: PMC3549826

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Source receipt: pubmed, retrieved 7 Sept 2026.

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