Article
A general model of codon bias due to GC mutational bias.
PloS one - 27 Oct 2010
Palidwor Gareth A, Perkins Theodore J, Xia Xuhua
Abstract excerpt
BACKGROUND: In spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been lacking. Because most amino acids allow synonymous GC content changing substitutions in the third codon position, the overall GC bias of a genome or genomic region is highly correlated with GC3, a measure of third position GC content. For individual...
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