Article
Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease.
BMC cancer - 12 Sept 2012
Skirnisdottir Ingiridur, Mayrhofer Markus, Rydåker Maria, Akerud Helena, Isaksson Anders
Abstract excerpt
BACKGROUND: Ovarian cancer is a heterogeneous disease and prognosis for apparently similar cases of ovarian cancer varies. Recurrence of the disease in early stage (FIGO-stages I-II) serous ovarian cancer results in survival that is comparable to those with recurrent advanced-stage disease. The aim of this study was to investigate if there are specific genomic aberrations that may explain recurrence and clinical...
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