Article
Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas
11 Jul 2005
Abstract excerpt
BACKGROUND AND AIMS: Hepatitis B virus (HBV) DNA integration into or close to cellular genes is frequently detected in HBV positive hepatocellular carcinomas (HCC). We have previously shown that viral integration can lead to aberrant target gene transcription. In this study, we attempted to investigate common pathways to hepatocarcinogenesis. METHODS: By using a modified Alu-polymerase chain reaction approach, we...
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