Article
Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.
BMC medical genomics - 6 Sept 2012
Tchou Julia, Kossenkov Andrew V, Chang Lisa, Satija Celine, Herlyn Meenhard, Showe Louise C, Puré Ellen
Abstract excerpt
BACKGROUND: Breast cancer is a heterogeneous disease for which prognosis and treatment strategies are largely governed by the receptor status (estrogen, progesterone and Her2) of the tumor cells. Gene expression profiling of whole breast tumors further stratifies breast cancer into several molecular subtypes which also co-segregate with the receptor status of the tumor cells. We postulated that cancer associated...
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