Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reciprocal changes in gene expression profiles of cocultured breast epithelial cells and primary fibroblasts

15 Jun 2009

Abstract excerpt

The importance of epithelial-stroma interaction in normal breast development and tumor progression has been recognized. To identify genes that were regulated by these reciprocal interactions, we cocultured a nonmalignant (MCF10A) and a breast cancer derived (MDA-MB231) basal cell lines, with fibroblasts isolated from breast benign-disease adjacent tissues (NAF) or with carcinoma-associated fibroblasts (CAF), in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related Molecular Pathways
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19530251
DOI: 10.1002/ijc.24646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reciprocal changes in gene expression profiles of cocultured breast epithelial cells and primary fibroblastsPMID 19530251Read ↗

Gene expression analysis of in vitro cocultures to study interactions between breast epithelium and stroma.Semantic proximity Read ↗

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.Semantic proximity Read ↗

Breast Carcinoma–Associated Fibroblasts and Their Counterparts Display Neoplastic-Specific ChangesSemantic proximity Read ↗

Biological Characteristics and Genetic Heterogeneity between Carcinoma-Associated Fibroblasts and Their Paired Normal Fibroblasts in Human Breast CancerSemantic proximity Read ↗

Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast.Semantic proximity Read ↗

Normal mammary fibroblasts induce reversion of the malignant phenotype in human primary breast cancer.Semantic proximity Read ↗

Gene Expression Profiling Reveals Cross-talk between Melanoma and Fibroblasts: Implications for Host-Tumor Interactions in MetastasisSemantic proximity Read ↗

Gene expression profile of normal and cancer-associated fibroblasts according to intratumoral inflammatory cells phenotype from breast cancer tissue.Semantic proximity Read ↗

Gap junction communication regulates luminal-myoepithelial crosstalk and cell differentiation in a bilayered human mammary epithelial cell modelSemantic proximity Read ↗

Genomics and proteomics approaches to the study of cancer-stroma interactionsSemantic proximity Read ↗

Collagen and fibronectin promote an aggressive cancer phenotype in breast cancer cells but drive autonomous gene expression patterns.Semantic proximity Read ↗

Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-cultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.