Article
Measuring ambiguity in HLA typing methods.
PloS one - 1 Jan 2012
Paunić Vanja, Gragert Loren, Madbouly Abeer, Freeman John, Maiers Martin
Abstract excerpt
In hematopoietic stem cell transplantation, donor selection is based primarily on matching donor and patient HLA genes. These genes are highly polymorphic and their typing can result in exact allele assignment at each gene (the resolution at which patients and donors are matched), but it can also result in a set of ambiguous assignments, depending on the typing methodology used. To facilitate rapid identification...
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