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Article

A Tool for the Assessment of HLA-DQ Heterodimer Variation in Hematopoietic Cell Transplantation.

Transplantation and cellular therapy - 1 Nov 2024

Sajulga Ray W, Bolon Yung-Tsi, Maiers Martin J, Petersdorf Effie W

Abstract excerpt

When optimizing transplants, clinical decision-makers consider HLA-A, -B, -C, -DRB1 (8 matched alleles out of 8), and sometimes HLA-DQB1 (10 out of 10) matching between the patient and donor. HLA-DQ is a heterodimer formed by the β chain product of HLA-DQB1 and an α chain product of HLA-DQA1. In addition to molecules defined by the parentally inherited cis haplotypes, α-β trans-dimerization is possible between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39151729
DOI: 10.1016/j.jtct.2024.08.006
PMCID: PMC11610517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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