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Article

Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data.

BMC bioinformatics - 30 May 2017

Schäfer Christian, Schmidt Alexander H, Sauter Jürgen

Abstract excerpt

BACKGROUND: Knowledge of HLA haplotypes is helpful in many settings as disease association studies, population genetics, or hematopoietic stem cell transplantation. Regarding the recruitment of unrelated hematopoietic stem cell donors, HLA haplotype frequencies of specific populations are used to optimize both donor searches for individual patients and strategic donor registry planning. However, the estimation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28558647
DOI: 10.1186/s12859-017-1692-y
PMCID: PMC5450239

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