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Article

Extensive natural variation for cellular hydrogen peroxide release is genetically controlled.

PloS one - 1 Jan 2012

Attar Homa, Bedard Karen, Migliavacca Eugenia, Gagnebin Maryline, Dupré Yann, Descombes Patrick, Borel Christelle, Deutsch Samuel, Prokisch Holger, Meitinger Thomas, Mehta Divya, Wichmann Erich, Delabar Jean Maurice, Dermitzakis Emmanouil T, Krause Karl-Heinz, Antonarakis Stylianos E

Abstract excerpt

Natural variation in DNA sequence contributes to individual differences in quantitative traits. While multiple studies have shown genetic control over gene expression variation, few additional cellular traits have been investigated. Here, we investigated the natural variation of NADPH oxidase-dependent hydrogen peroxide (H(2)O(2) release), which is the joint effect of reactive oxygen species (ROS) production,...

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Identifiers

PMID: 22952707
DOI: 10.1371/journal.pone.0043566
PMCID: PMC3430705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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