Article

Pooled CRISPR screens identify genes and non-coding genomic regions that regulate red blood cell density

2025-09-21

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies have identified >1,000 loci associated with clinically important red blood cell (RBC) traits, such as hemoglobin concentration and cell volume. However, few of these associations have been characterized at the molecular level such that most causal genes and variants remain elusive. Here, we performed pooled CRISPR screens in an erythroid cell line to identify gene...

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Literature Corpus work: 6be50a99-ff0c-5eae-88e0-9fc94a15af04
DOI: 10.1101/2025.09.20.677403

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