Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small- and large-effect quantitative trait locus interactions underlie variation in yeast sporulation efficiency.

Genetics - 1 Nov 2012

Lorenz Kim, Cohen Barak A

Abstract excerpt

Quantitative trait loci (QTL) with small effects on phenotypic variation can be difficult to detect and analyze. Because of this a large fraction of the genetic architecture of many complex traits is not well understood. Here we use sporulation efficiency in Saccharomyces cerevisiae as a model complex trait to identify and study small-effect QTL. In crosses where the large-effect quantitative trait nucleotides...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Epistasis, Genetic
Share to Hemizygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lod Score

Share to Polymorphism, Genetic

Share to Quantitative Trait Loci

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 22942125
DOI: 10.1534/genetics.112.143107
PMCID: PMC3522155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small- and large-effect quantitative trait locus interactions underlie variation in yeast sporulation efficiency.PMID 22942125Read ↗

Small effect-size mutations cumulatively affect yeast quantitative traitsSemantic proximity Read ↗

Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression.Semantic proximity Read ↗

Rare variants contribute disproportionately to quantitative trait variation in yeast.Semantic proximity Read ↗

Dissection of genetically complex traits with extremely large pools of yeast segregants.Semantic proximity Read ↗

Genetic interactions contribute less than additive effects to quantitative trait variation in yeast.Semantic proximity Read ↗

Four linked genes participate in controlling sporulation efficiency in budding yeast.Semantic proximity Read ↗

Rare variants contribute disproportionately to quantitative trait variation in yeastSemantic proximity Read ↗

Advances in quantitative trait analysis in yeast.Semantic proximity Read ↗

The genotype-phenotype map of yeast complex traits: basic parameters and the role of natural selection.Semantic proximity Read ↗

Complex genetic interactions in a quantitative trait locus.Semantic proximity Read ↗

Dissecting the architecture of a quantitative trait locus in yeast.Semantic proximity Read ↗

Gene-gene and gene-environment interactions in complex traits in yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.