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Article

Codons support the maintenance of intrinsic DNA polymer flexibility over evolutionary timescales.

Genome biology and evolution - 1 Jan 2012

Babbitt G A, Schulze K V

Abstract excerpt

Despite our long familiarity with how the genetic code specifies the amino acid sequence, we still know little about why it is organized in the way that it is. Contrary to the view that the organization of the genetic code is a "frozen accident" of evolution, recent studies have demonstrated that it is highly nonrandom, with implications for both codon assignment and usage. We hypothesize that this inherent...

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PMID: 22936074
DOI: 10.1093/gbe/evs073
PMCID: PMC3468960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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