Article
Loss of heterozygosity on chromosome 11p13 in primary bladder carcinoma.
Human genetics - 1 Jun 1993
Shipman R, Schraml P, Colombi M, Raefle G, Ludwig C U
Abstract excerpt
Although the occurrence of bladder cancer is common, the molecular events underlying the pathogenesis of this cancer remain ill-defined. A loss of heterozygosity (LOH) at specific chromosomal loci may predispose individuals to the development of bladder cancer but this has not been examined in de...
Topics
- Alleles
- Chromosomes, Human, Pair 11
- DNA, Neoplasm
- Gene Deletion
- Genetic Markers
- Humans
- Polymorphism, Restriction Fragment Length
- Urinary Bladder Neoplasms
