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Article

Temporal association of HLA-B81:01- and HLA-B39:10-mediated HIV-1 p24 sequence evolution with disease progression.

Journal of virology - 1 Nov 2012

Ntale R S, Chopera D R, Ngandu N K, Assis de Rosa D, Zembe L, Gamieldien H, Mlotshwa M, Werner L, Woodman Z, Mlisana K, Abdool Karim S, Gray C M, Williamson C

Abstract excerpt

HLA-B*81:01 and HLA-B*39:10 alleles have been associated with viremic control in HIV-1 subtype C infection. Both alleles restrict the TL9 epitope in p24 Gag, and cytotoxic-T-lymphocyte (CTL)-mediated escape mutations in this epitope have been associated with an in vitro fitness cost to the virus....

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Identifiers

PMID: 22933291
DOI: 10.1128/JVI.00539-12
PMCID: PMC3486481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22933291-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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