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Article

High order interactions of xenobiotic metabolizing genes and P53 codon 72 polymorphisms in acute leukemia.

Environmental and molecular mutagenesis - 1 Oct 2012

Chauhan Pradeep Singh, Ihsan Rakhshan, Mishra Ashwani Kumar, Yadav Dhirendra Singh, Saluja Sumita, Mittal Vishakha, Saxena Sunita, Kapur Sujala

Abstract excerpt

Polymorphisms in xenobiotic metabolizing genes are associated with altered metabolism of carcinogens in acute leukemia (AL). This study applied two data mining approaches to explore potential interactions among P53 and xenobiotic metabolizing genes in 230 AL patients [131 acute myeloid leukemia (AML) and 99 acute lymphoblastic leukemia (ALL)] and 199 controls. Individually, none of the genotypes showed...

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Source

Identifiers

PMID: 22930568
DOI: 10.1002/em.21723

Genes

EPHX1
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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