Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2007

Rebbeck Timothy R, Troxel Andrea B, Walker Amy H, Panossian Saarene, Gallagher Stephen, Shatalova Ekaterina G, Blanchard Rebecca, Norman Sandra, Bunin Greta, DeMichele Angela, Berlin Michelle, Schinnar Rita, Berlin Jesse A, Strom Brian L

Abstract excerpt

Estrogen exposures have been associated with breast cancer risk, and genes involved in estrogen metabolism have been reported to mediate that risk. Our goal was to better understand whether combinations of candidate estrogen metabolism genotypes are associated with breast cancer etiology. A population-based case-control study in three counties of the Philadelphia Metropolitan area was undertaken. We evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogens
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Logistic Models

Share to Pennsylvania

Share to Population Surveillance

Share to Postmenopause

Share to Registries

Source

Identifiers

PMID: 17372239
DOI: 10.1158/1055-9965.EPI-06-0800

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pairwise combinations of estrogen metabolism genotypes in postmenopausal breast cancer etiology.PMID 17372239Read ↗

Estrogen-related genes and their contribution to racial differences in breast cancer risk.Semantic proximity Read ↗

Estrogen metabolism-related genes and breast cancer risk: the multiethnic cohort study.Semantic proximity Read ↗

Evaluation of breast cancer risk in a multigenic model including low penetrance genes involved in xenobiotic and estrogen metabolisms.Semantic proximity Read ↗

Role of cytochrome P450 genes in breast cancer etiology and treatment: effects on estrogen biosynthesis, metabolism, and response to endocrine therapy.Semantic proximity Read ↗

Genetic polymorphisms, the metabolism of estrogens and breast cancer: a review.Semantic proximity Read ↗

Possible risk modification by polymorphisms of estrogen metabolizing genes in familial breast cancer susceptibility in an Indian population.Semantic proximity Read ↗

Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility.Semantic proximity Read ↗

Estrogen sulfation genes, hormone replacement therapy, and endometrial cancer risk.Semantic proximity Read ↗

Estrogen bioactivation, genetic polymorphisms, and ovarian cancer.Semantic proximity Read ↗

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Semantic proximity Read ↗

Breast cancer risk associated with genotype polymorphism of the catechol estrogen-metabolizing genes: a multigenic study on cancer susceptibility.Semantic proximity Read ↗

Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.