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Article

Polymorphisms in xenobiotic-metabolizing genes and the risk of chronic lymphocytic leukemia and non-Hodgkin's lymphoma in adult Russian patients.

American journal of hematology - 1 Apr 2008

Gra Olga A, Glotov Andrey S, Nikitin Eugene A, Glotov Oleg S, Kuznetsova Viktoria E, Chudinov Alexander V, Sudarikov Andrey B, Nasedkina Tatyana V

Abstract excerpt

Polymorphisms in genes coding xenobiotic-metabolizing enzymes are considered as risk factors modifying susceptibility to cancer. We developed a biochip for the analysis of 18 mutations in 10 genes of metabolizing system: CYP1A1, CYP2D6, GSTT1, GSTM1, MTHFR, MTRR, NQO1, CYP2C9, CYP2C19, and NAT2. Using allele-specific hybridization on the biochip 76 T-cell non-Hodgkin's lymphoma (NHL) patients, 83 B-cell chronic...

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Source

Identifiers

PMID: 18061941
DOI: 10.1002/ajh.21113

Genes

GSTM1
GSTT1
MTHFR
MTRR
NAT2
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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