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Article

Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.

Molecular carcinogenesis - 1 May 2011

Goode Ellen L, White Kristin L, Vierkant Robert A, Phelan Catherine M, Cunningham Julie M, Schildkraut Joellen M, Berchuck Andrew, Larson Melissa C, Fridley Brooke L, Olson Janet E, Webb Penelope M, Chen Xiaoqing, Beesley Jonathan, Chenevix-Trench Georgia, Sellers Thomas A

Abstract excerpt

Because selected xenobiotic-metabolizing enzymes process pro-carcinogens that could initiate ovarian carcinogenesis, we hypothesized that single nucleotide polymorphisms (SNPs) in the genes encoding xenobiotic-metabolizing enzymes are associated with risk of ovarian cancer. Cases with invasive ep...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 21480392
DOI: 10.1002/mc.20714
PMCID: PMC3115705

Genes

ADH4
EPHX1
NQO1
GSTP1
NAT2
NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21480392-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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