Article
Association of Fcγ receptor IIIa genotype with the rate of HIV infection after gp120 vaccination.
Blood - 4 Oct 2012
Forthal Donald N, Gabriel Erin E, Wang Angela, Landucci Gary, Phan Tran B
Abstract excerpt
We determined whether polymorphisms in Fcγ receptor (FcγR) IIa or FcγRIIIa genes were associated with outcomes in Vax004, a trial testing recombinant gp120 vaccination in preventing sexually acquired HIV infection. Male subjects (n = 1725), including infected and uninfected vaccinees and placebo recipients, were genotyped. We observed no association between FcγRIIa genotype and infection rate in vaccinees or...
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