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Article

Case-only method for cause-specific hazards models with application to assessing differential vaccine efficacy by viral and host genetics.

Biostatistics (Oxford, England) - 1 Jan 2014

Dai James Y, Li Shuying S, Gilbert Peter B

Abstract excerpt

Cause-specific proportional hazards models are commonly used for analyzing competing risks data in clinical studies. Motivated by the objective to assess differential vaccine protection against distinct pathogen types in randomized preventive vaccine efficacy trials, we present an alternative case-only method to standard maximum partial likelihood estimation that applies to a rare failure event, e.g. acquisition...

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Identifiers

PMID: 23813283
DOI: 10.1093/biostatistics/kxt018
PMCID: PMC3862206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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