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Article

Lymphocytes from young healthy persons carrying the ApoE4 allele overexpress stress-related proteins involved in the pathophysiology of Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Badia Mari-Carmen, Lloret Ana, Giraldo Esther, Dasí Francisco, Olaso Gloria, Alonso Maria-Dolores, Viña Jose

Abstract excerpt

Apolipoprotein E4 (ApoE4) is a major genetic risk factor for the development of Alzheimer's disease (AD). The aim of this work was to find if carrying ApoE4 alleles correlates with molecular changes associated with specific processes involved in AD pathophysiology and whether they are useful as early biomarkers of AD. Fifty four young healthy adults (aged 20-55) were recruited. Of these, 33 carried at least one...

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Source

Identifiers

PMID: 22914590
DOI: 10.3233/JAD-2012-120973

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RCAN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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