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Article

Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype.

Archives of neurology - 1 Jun 2012

Ringman John M, Elashoff David, Geschwind Daniel H, Welsh Brian T, Gylys Karen H, Lee Cathy, Cummings Jeffrey L, Cole Greg M

Abstract excerpt

OBJECTIVE: To study the effect of familial Alzheimer disease (FAD) mutations and APOE genotype on plasma signaling protein levels. DESIGN: Cross-sectional comparison of plasma levels of 77 proteins measured using multiplex immune assays. SETTING: A tertiary referral dementia research center. PARTICIPANTS: Thirty-three persons from families harboring PSEN1 or APP mutations, aged 19 to 59 years. MAIN OUTCOME...

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Source

Open in PubMed Open full text

Identifiers

PMID: 22689192
DOI: 10.1001/archneurol.2012.277
PMCID: PMC3668092

Genes

APOE
APP
PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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