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Age‐related changes in gene expression are accelerated in Alzheimer's disease

21 Mar 2011

Abstract excerpt

In the normal brain, age is associated with changes in gene expression. Age is also a prominent risk factor for Alzheimer's disease (AD), where clinical features are similar to age-related decreases in cognitive performance. We hypothesized that some age-related changes in gene expression are accelerated in AD patients. To study this, we selected 10 candidate genes earlier shown by microarray analysis to be...

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PMID: 21425351
DOI: 10.1002/syn.20933

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