Article
Two-stage normalization using background intensities in cDNA microarray data.
BMC bioinformatics - 21 Jul 2004
Yoon Dankyu, Yi Sung-Gon, Kim Ju-Han, Park Taesung
Abstract excerpt
BACKGROUND: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the measured gene expression levels. Normalization plays an important role in the earlier stage of microarray data analysis. The subsequent analysis results are highly dependent on normalization. One major source of variation is the background...
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