Article
Cross phenotype normalization of microarray data.
Frontiers in bioscience (Elite edition) - 1 Jan 2010
Xuan Jianhua, Wang Yue, Hoffman Eric, Clarke Robert
Abstract excerpt
Normalization is a prerequisite for almost all follow-up steps in microarray data analysis. Accurate normalization across different experiments and phenotypes assures a common base for comparative yet quantitative studies using gene expression data. In this paper, we report a comparison study of four normalization approaches, namely, linear regression (LR), Loess regression, invariant ranking (IR) and iterative...
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