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Article

Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution.

Nature communications - 1 Nov 2011

Carmi Shai, Church George M, Levanon Erez Y

Abstract excerpt

Retrotransposons had an important role in genome evolution, including the formation of new genes and promoters and the rewiring of gene networks. However, it is unclear how such a repertoire of functions emerged from a relatively limited number of source sequences. Here we show that DNA editing, an antiviral mechanism, accelerated the evolution of mammalian genomes by large-scale modification of their...

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PMID: 22044998
DOI: 10.1038/ncomms1525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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