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Article

Footprint of APOBEC3 on the genome of human retroelements.

Journal of virology - 1 Jul 2013

Anwar Firoz, Davenport Miles P, Ebrahimi Diako

Abstract excerpt

Almost half of the human genome is composed of transposable elements. The genomic structures and life cycles of some of these elements suggest they are a result of waves of retroviral infection and transposition over millions of years. The reduction of retrotransposition activity in primates compared to that in nonprimates, such as mice, has been attributed to the positive selection of several antiretroviral...

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Identifiers

PMID: 23698293
DOI: 10.1128/JVI.00298-13
PMCID: PMC3700199

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