Role of autologous hematopoietic stem cell transplantation according to the NPM1/FLT3-ITD molecular status for cytogenetically normal AML patients: a GOELAMS study.

doi:10.1002/ajh.23311

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Article

Role of autologous hematopoietic stem cell transplantation according to the NPM1/FLT3-ITD molecular status for cytogenetically normal AML patients: a GOELAMS study.

American journal of hematology - 1 Dec 2012

Guièze Romain, Cornillet-Lefebvre Pascale, Lioure Bruno, Blanchet Odile, Pigneux Arnaud, Recher Christian, Bonmati Caroline, Fegueux Nathalie, Bulabois Claude-Eric, Bouscary Didier, Vey Norbert, Delain Martine, Turlure Pascal, Himberlin Chantal, Harousseau Jean-Luc, Dreyfus Francois, Béné Marie C, Ifrah Norbert, Chevallier Patrice

Abstract excerpt

The choice of postremission therapy for acute myeloid leukemia (AML) patients is now based on the blasts' cytogenetic and molecular profile. However, the potential benefit of autologous hematopoietic stem cell transplantation (auto-HSCT) according to the NPM1/FLT3-ITD status has been poorly studied in AML patients with a normal karyotype (NK). Therefore, we evaluated the NPM1/FLT3-ITD molecular status in 135...

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Identifiers

PMID: 22911473
DOI: 10.1002/ajh.23311

Genes

FLT3
NPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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