Article
Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation.
Blood - 22 Oct 2015
Schmid Christoph, Labopin Myriam, Socié Gerard, Daguindau Etienne, Volin Liisa, Huynh Anne, Bourhis Jean Henri, Milpied Noel, Cornelissen Jan, Chevallier Patrice, Maertens Johan, Jindra Pavel, Blaise Didier, Lenhoff Stig, Ifrah Norbert, Baron Frédéric, Ciceri Fabio, Gorin Claude, Savani Bipin, Giebel Sebastian, Polge Emmanuelle, Esteve Jordi, Nagler Arnon, Mohty Mohamad
Abstract excerpt
To analyze the influence of distinct combinations of molecular aberrations on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) for cytogenetically normal acute myeloid leukemia (CN-AML), a retrospective registry analysis was performed on 702 adults undergoing HSCT in first complete remission (CR). Patients were grouped according to presence or absence of NPM1 mutations (NPM1(mut)) and FLT3...
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